Normalization of methotrexate-induced high levels of serum transaminases after ursodeoxycholic acid administration in a rheumatoid arthritis patient SIR, Administration of ursodeoxycholic acid (UDCA) can improve liver function in the course of several hepatic

inflammatory process improves, FDG uptake should be diminished, at least in the affected vessels. This was confirmed in the two patients for whom we have a follow-up F18-FDG-PET. Nevertheless, this pathophysiological basis can cause some false-positive results, as FDG uptake can occur in atherosclerotic lesions with an accumulation of inflammatory cells. Usually these images are less clearly positive and the distribution is different. F18-FDG-PET not only seems to be a useful tool in the diagnosis of giant cell arteritis itself, but it also seems to be helpful in the evaluation of the extent and activity of the disease.